Inflammation Is Now Recognized as a Primary Aging Signal

For decades, inflammation was viewed mainly as an immune response to injury or infection.

In 2025, researchers now describe chronic low-grade inflammation as one of the strongest predictors of biological age.

New research links persistent inflammation to:

  • accelerated cellular aging

  • mitochondrial dysfunction

  • hormonal signaling disruption

  • tissue degeneration

  • immune system exhaustion

Scientists increasingly refer to this state as “inflammaging”, a slow, systemic process that quietly advances aging even in people who appear outwardly healthy.

Inflammation is no longer seen as a side effect of aging.

It is considered a driver of aging itself.

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